Down-regulation of Gal 3-O-sulfotransferase-2 (Gal3ST-2) Expression in Human Colonic Non-mucinous Adenocarcinoma
نویسندگان
چکیده
منابع مشابه
Ectopic expression of a GlcNAc 6-O-sulfotransferase, GlcNAc6ST-2, in colonic mucinous adenocarcinoma.
The content of sulfated glycans having 6-O-sulfated GlcNAc residues alters in the course of colonic carcinogenesis. We previously characterized two GlcNAc 6-O-sulfotransferases (SulTs), SulT-a and -b, expressed in colonic normal tissues and adenocarcinomas [Seko et al. (2000) Glycobiology, 10, 919-929]. Levels of the enzymatic activities of SulT-a in normal colonic mucosa are higher than those ...
متن کاملMucinous and Non-Mucinous Adenocarcinoma in Colorectal Cancer Patients
Background: The oncologic behavior of mucinous adenocarcinoma (MA) of colorectal differs from non-mucinous adenocarcinoma (NMA). MA is more advanced at diagnosis and has a poorer prognosis than NMA. We aimed to evaluate prognostic factors and survival rate in patients with MA compared with NMA in Western Iran. Methods: During 2008-2015 in a retrospective study, 83 patients with CRC referred to...
متن کاملDown-Regulation of Lipocalin 2 Expression in Mouse Testis after Exposure to Electromagnetic Field
Background: The effects of electromagnetic field (EMF) on reproductive system have been of critical concern for a long time. It has been shown that the EMF can adversely affect testicular cells and tissue and decrease male fertility. The most important determinants of male fertility are sperm development and motility, which are affected by changes in several factors including lipocalin 2 protei...
متن کاملAnalysis of TP53 Codon 72 Polymorphism in Mucinous and Non-Mucinous Colorectal Adenocarcinoma in Isfahan, Iran
Background: The tumor suppressor gene TP53 (alias p53) located on chromosome 17 is involved in various cancers. Case-control studies have shown that p53 codon 72 polymorphism modulates the prognosis and susceptibility to various malignancies. We undertook the present study to explore a possible association between mucinous and non-mucinous adenocarcinomas with different genotypes or alleles at ...
متن کاملO-2: The Effect of Age on the Expression of Apoptosis Biomarkers in Human Spermatozoa
Background: The negative impact of age on reproductive success has been well demonstrated for women, but age-related changes in the male reproductive system appear to be more subtle. Diminishing testicular function is indicated by a decline in testosterone levels, accompanied by an increase in gonadotropins. Some studies have shown increased age-related numerical and structural sperm chromosoma...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Cancer Research
سال: 2002
ISSN: 0910-5050
DOI: 10.1111/j.1349-7006.2002.tb01285.x